The Tuberoinfundibular Pathway: Balancing Dopamine and Serotonin in Prolactin Regulation

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In earlier posts we have discussed the mesolimbic, mesocortical and nigrostriatal pathways of the brain. Today, we will discuss yet another: the tuberinfundibular pathway which stands out for its role in the regulation of prolactin, a hormone vital for milk production post-childbirth among other functions.

In this post, we will discuss the anatomy, physiology and implications for practice associated with this pathway.

Anatomy: Mapping the Pathway The tuberoinfundibular pathway originates in the hypothalamus, specifically from the arcuate and periventricular nuclei.